Bitola is a city in the southwestern part of North Macedonia. It is located in the southern part of the Pelagonia valley, surrounded by the Baba, Nidže and Kajmakčalan mountain ranges, 14 kilometres north of the Medžitlija-Níki border crossing with Greece. The city stands at an important junction connecting the south of the Adriatic Sea region with the Aegean Sea and Central Europe, and is an administrative, cultural, industrial, commercial, and educational centre. It has been known since the Ottoman period as "The City of The Consuls", since many European countries had consulates in Bitola.

Bitola, known during the Ottoman Empire as Manastir/Monastir, is one of the oldest cities in North Macedonia. It was founded as Heraclea Lyncestis in the middle of the 4th century BC by Philip II of Macedon. The city was the last capital of Ottoman Rumelia, from 1836 to 1867. According to the 2002 census, Bitola is the second-largest city in the country.

Bitola is the economic and industrial center of southwestern North Macedonia. Many of the largest companies in the country are based in the city. The Pelagonia agricultural combine is the largest producer of food in the country. The Streževo water system is the largest in North Macedonia and has the best technological facilities. The three thermoelectric power stations of REK Bitola produce nearly 80% of electricity in the state. The Frinko refrigerate factory was a leading electrical and metal company. Bitola also has significant capacity in the textile and food industries.

Bitola has been part of the UNESCO Creative Cities Network since December 2015.

Skopje is the capital and largest city of the Republic of Macedonia. It is the country's political, cultural, economic, and academic center. Skopje is located on the upper course of the Vardar River, and is located on a major north-south Balkan route between Belgrade and Athens. It was known in the Roman period under the name Scupi.

The territory of Skopje has been inhabited since at least 4000 BC; remains of Neolithic settlements have been found within the old Kale Fortress that overlooks the modern city centre. On the eve of the 1st century AD, the settlement was seized by the Romans and became a military camp. When the Roman Empire was divided into eastern and western halves in 395 AD, Scupi came under Byzantine rule from Constantinople.

Being the capital of the Republic of Macedonia, Skopje is home to the largest cultural institutions of the country, such as the National and University Library "St. Kliment of Ohrid", the Macedonian Academy of Sciences and Arts, the National Theatre, the National Philarmonic Orchestra and the Macedonian Opera and Ballet. Among the local institutions are the Brothers Miladinov Library which has more than a million documents, the Cultural Information Centre which manages festivals, exhibitions and concerts, and the House of Culture Kočo Racin which is dedicated to contemporary art and young talents.

The Skopje Jazz Festival has been held annually in October since 1981. It is part of the European Jazz Network and the European Forum of World Wide Festivals. The artists' profiles include fusion, acid jazz, Latin jazz, smooth jazz, and avant-garde jazz. Ray Charles, Tito Puente, Gotan Project, Al Di Meola, Youssou N'Dour, among others, have performed at the festival. Another music festival in Skopje is the Blues and Soul Festival. It is a relatively new event in the Macedonian cultural scene that occurs every summer in early July. Past guests include Larry Coryell, Mick Taylor & the All-Stars Blues Band, Candy Dulfer & Funky Stuff, João Bosco, The Temptations, Tolo Marton Trio, Blues Wire, and Phil Guy.